Lyz2-Cre
2022-11-17
B6.129P2-Lyz2tm1(cre)Ifo/J
鍝佺郴绶ㄨ櫉锛�GAP1052
鍝佺郴绨$ū锛�Lyz2-Cre | Also Known As: LysM-cre
鍝佺郴鐗归粸(di菐n)锛�
LysM-cre 鏄湪鑿岄叾2鍩哄洜 (Lyz2) 鐨勭涓€鍊嬬法纰� ATG 鍚庢彃鍏� Cre 閲嶇祫閰�锛� 鐮村浜嗗収(n猫i)婧愭€� Lyz2 鍩哄洜鍔熻兘锛� LysMcre 灏忛紶涓昏鐢ㄤ簬灏嶉楂撶窗(x矛)鑳炶瓬绯伙紙鍠牳绱�(x矛)鑳�銆佹垚鐔熷法鍣窗(x矛)鑳炲拰绮掔窗(x矛)鑳烇級鍜屽厛澶╁厤鐤弽鎳�(y墨ng)鐨� Cre-loxp绯荤当(t菕ng)鐮旂┒浣跨敤銆�
閬哄偝瀛�(xu茅)淇℃伅锛�
閬哄偝鑳屾櫙锛�C57BL/6J
鍝佺郴椤炲瀷锛�Targeted
鐩搁棞(gu膩n)鍩哄洜锛�Lyz2-cre
椋奸(y菐ng)淇℃伅锛�
閰嶇箒绛栫暐锛�
Homozygote x Homozygote
閰嶇箒鐗规€э細
瑭插皬榧犲彲浠ョ敤绱斿悎瀛愮箒娈�锛屾瘺鑹茬偤榛戣壊銆�
lyz2-cre lysm-cre
鎳�(y墨ng)鐢ㄩ牁(l菒ng)鍩�锛�
1銆�鐢ㄤ簬楠ㄩ珦绱�(x矛)鑳炶瓬绯伙紙鍠牳绱�(x矛)鑳�銆佹垚鐔熷法鍣窗(x矛)鑳炲拰绮掔窗(x矛)鑳烇級鍜屽厛澶╁厤鐤弽鎳�(y墨ng)鐨� Cre-lox绯荤当(t菕ng)鐮旂┒銆�
鍙冭€冩枃鐛�(xi脿n)锛�
1銆�Conditional gene targeting in macrophages and granulocytes using LysMcre mice.Clausen BE , et al.Transgenic Res 8(4):265-77